کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5521143 | 1401250 | 2017 | 9 صفحه PDF | دانلود رایگان |
- Magnetic nanoparticles with multi-functionality can used for theranostic applications.
- Various magnetic nanoparticle mediated therapeutic strategies are summarized.
- Magnetic hyperthermia and targeting is an alternative strategy to treat prostate cancer.
- Targeted magnetic nanoparticles delivery of therapeutics is still warranted.
Magnetic nanoparticles (MNPs) play a vital role for improved imaging applications. Recently, a number of studies demonstrate MNPs can be applied for targeted delivery, sustained release of therapeutics, and hyperthermia. Based on stable particle size and shape, biocompatibility, and inherent contrast enhancement characteristics, MNPs have been encouraged for pre-clinical studies and human use. As a theranostic platform development, MNPs need to balance both delivery and imaging aspects. Thus, this review provides significant insight and advances in the theranostic role of MNPs through the documentation of unique magnetic nanoparticles used in prostate cancer, their interaction with prostate cancer cells, in vivo fate, targeting, and biodistribution. Specific and custom-made applications of various novel nanoformulations in prostate cancer are discussed.
Journal: Drug Discovery Today - Volume 22, Issue 8, August 2017, Pages 1233-1241