کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5548601 1556547 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Cognitive eloquence in neurosurgery: Insight from graph theoretical analysis of complex brain networks
ترجمه فارسی عنوان
اصطلاح شناختی در جراحی مغز و اعصاب: بینش از تجزیه و تحلیل نظری گراف شبکه های پیچیده مغز
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی زیست شناسی تکاملی
چکیده انگلیسی

The structure and function of the brain can be described by complex network models, and the topological properties of these models can be quantified by graph theoretical analysis. This has given insight into brain regions, known as hubs, which are critical for integrative functioning and information transfer, both fundamental aspects of cognition. In this manuscript a hypothesis is put forward for the concept of cognitive eloquence in neurosurgery; that is regions (cortical, subcortical and white matter) of the brain which may not necessarily have readily identifiable neurological function, but if injured may result in disproportionate cognitive morbidity. To this end, the effects of neurosurgical resection on cognition is reviewed and an overview of the role of complex network analysis in the understanding of brain structure and function is provided. The literature describing network, behavioral, and cognitive effects resulting from lesions to, and disconnections of, centralized hub regions will be emphasized as evidence for the espousal of the concept of cognitive eloquence.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Medical Hypotheses - Volume 98, January 2017, Pages 49-56
نویسندگان
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