کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5551029 1402937 2017 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
New psychoactive substances of natural origin: A brief review
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک دانش تغذیه
پیش نمایش صفحه اول مقاله
New psychoactive substances of natural origin: A brief review
چکیده انگلیسی


- New psychoactive substances, which are mostly not controlled by the UN conventions, are a new threat to global public health.
- Although most NPS are synthetic chemicals, they are usually derived from natural origin.
- The chemistry, pharmacology and toxicology of five NPS of natural origin, khat, kratom, salvia, magic mushrooms and mandrake, are reviewed.

Plant-based drugs of abuse are as old as recorded human history. Although traditional addictive substances, such as opium, cannabis and coca, have been controlled by the United Nations anti-drug conventions, many, if not most, natural plants with addictive or abuse liability remain elusive. Therefore, the United Nations Office on Drugs and Crime (UNODC) has warned the emerging threat from new psychoactive substances (NPS), which are mostly derived or modified from the constituents of natural origin. For example, synthetic cannabinoids and synthetic cathinones are derived from the cannabis and khat plant, respectively. In this review, we briefly discussed the chemistry, pharmacology and toxicology of five common NPS of natural origin, i.e., khat, kratom, salvia, magic mushroom and mandrake. Through the review, we hope that professionals and general public alike can pay more attention to the potential problems caused by natural NPS, and suitable control measures will be taken.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Food and Drug Analysis - Volume 25, Issue 3, July 2017, Pages 461-471
نویسندگان
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