کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5553483 1557955 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tithonia diversifolia saponin-blood lipid interaction and its influence on immune system of normal wistar rats
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی تومور شناسی
پیش نمایش صفحه اول مقاله
Tithonia diversifolia saponin-blood lipid interaction and its influence on immune system of normal wistar rats
چکیده انگلیسی

This study investigated the effect of saponins (20-100 mg/kg) from Tithonia diversifolia leaf (STD) on the liver, kidney, heart, lipid profile and hematological parameters of normal rats. The results showed that STD (20-100 mg/kg) though caused a slight increase in the liver, heart and kidney activity of ALT, AST, ALP and GGT (p < 0.05), did not result in corresponding increase in the serum level of these enzymes. A significant reduction in the level of triglycerides, LDL and cholesterol, creatinine, urea, LDH, PCV and hemoglobin were observed with a concomitant increase in HDL, white blood cell and lymphocyte. These study demonstrated the role of STD in enhancing immune response and in reducing cholesterol and triglycerides in normal rats at studied dosages.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Biomedicine & Pharmacotherapy - Volume 87, March 2017, Pages 589-595
نویسندگان
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