کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5553900 1403019 2017 12 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
A Feasibility Trial of Home Administration of Intranasal Vaccine by Parents to Eligible Children
ترجمه فارسی عنوان
آزمایش امکان سنجی استفاده از واکسن اینترناسال توسط والدین به کودکان واجد شرایط
کلمات کلیدی
فرزندان، آنفلوآنزا، داخل بینی، واکسن آنفلوآنزا ضعیف شده زندگی می کند والدین، خود مدیریت،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پزشکی و دندانپزشکی (عمومی)
چکیده انگلیسی

PurposeIntranasal vaccines are being developed for protection against many different infectious agents. The currently available intranasal live attenuated influenza vaccine (LAIV) is only approved for administration by medical personnel. We conducted a pilot study to investigate the feasibility of training parents to give LAIV to their own children.MethodsSubjects were recruited from several sources: a university-based outpatient clinic, university employee e-mail announcement, and direct referrals from study subjects. After confirming eligibility to receive LAIV, consented parents were trained by viewing a video with the study staff. LAIV was provided in a cooler with instructions to vaccinate within 24 hours. Telephone follow-up was conducted to confirm proper administration and to assess parental attitudes about home administration. At season's end, immunization registry and hospital records were reviewed to confirm no additional doses were given.FindingsTwenty-seven families with 41 children were enrolled. All participants successfully administered LAIV to their children, and all preferred or strongly preferred home administration to an office visit for getting vaccinated. Two families stated that without this option they would not have otherwise vaccinated their children. Adverse events were minor. All patients had their state vaccine registries accurately updated and none received duplicate doses. Upon review, no reimbursement was received for vaccination.ImplicationsHome administration of intranasal LAIV was successful and well received. This option could be used in the future for LAIV or other intranasal vaccines as a way to increase vaccination rates and convenience for parents. ClinicalTrials.gov identifier: NCT01938170.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Therapeutics - Volume 39, Issue 1, January 2017, Pages 204-211.e4
نویسندگان
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