Chronic Recurrent Multifocal Osteomyelitis in a 5Â Year Old

Chronic recurrent multifocal osteomyelitis (CRMO) is an autoinflammatory disease that presents with focal bone lesions. CRMO is a diagnosis of exclusion and can be quite challenging to promptly establish an accurate diagnosis. CRMO can present and imitate concerning deteriorating illnesses, such as acute osteomyelitis and neoplasm. A thorough workup is necessary to eliminate any life-threatening illnesses. Having sufficient knowledge about CRMO including prevalence, clinical characteristics, familiarity with image findings on radiography, bone scans, and magnetic resonance imaging, as well as preferred treatment options, will ultimately help provide patients with the best potential outcomes.