کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5575535 | 1403972 | 2017 | 13 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Intérêt du suivi thérapeutique pharmacologique dans le cadre des infections pulmonaires
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کلمات کلیدی
Infections pulmonairesPharmacodynamie - داروسازیPulmonary infections - عفونت های ریویAnti-infective agents - عوامل ضد عفونیPharmacodynamics - فارماکودینامیکPharmacokinetics - فارماکوکینتیکpharmacocinétique - فارماکوکینتیکtherapeutic drug monitoring - نظارت بر دارودرمانیSuivi thérapeutique pharmacologique - نظارت فارماکولوژیک درمانی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Pulmonary infections are common and caused by a wide range of viruses, bacteria, parasites and fungi. They consist of lower respiratory tract infections with community and hospital acquired acute pneumonia, bronchitis, lung abscess, fungal infections and tuberculosis. The management of these infections should be based on guidelines that take into account the microorganisms most frequently involved as a basis for empirical treatment, with identification of causative microorganisms allowing targeted treatments. The patient's immune status, physiological changes leading to changes in pharmacokinetics, and the characteristics of drugs may result in a microbiological and/or clinical failure when using standard doses. Knowledge of these elements is essential for optimal management. The goal of therapeutic drug monitoring is to use drug concentrations and pharmacokinetic/pharmacodynamic objectives to manage a patient's medication regimen, optimize outcome and prevent resistance or toxicity. To make the best use of the resources, it is not possible to carry out systematic therapeutic drug monitoring. We need to define drugs and patients where there is most likely to be benefit from therapeutic drug monitoring. This must be a part of a comprehensive approach to patient care.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revue des Maladies Respiratoires - Volume 34, Issue 6, June 2017, Pages 693-705
Journal: Revue des Maladies Respiratoires - Volume 34, Issue 6, June 2017, Pages 693-705
نویسندگان
C. Padoin,