کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5583207 1567669 2018 6 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله
High-flow oxygen therapy in immunocompromised patients with acute respiratory failure: A review and meta-analysis
ترجمه فارسی عنوان
اکسیژن جریان بالای خون در بیماران مبتلا به نارسایی حاد تنفسی مبتلا به آسیب های ایمنی: بررسی و متاآنالیز می شود
کلمات کلیدی
ARF؛ نارسایی حاد تنفسی؛ CIs؛ فاصله اطمینان؛ HFNC؛ کانولای بینی بالا جریان؛ ICU؛ واحد مراقبت های ویژه؛ IQR؛ محدوده میان فاصله ای؛ MD؛ میانگین تفاوت ها؛ NIV؛ تهویه غیر تهاجمی RCTs؛ آزمایشات تصادفی کنترل شده؛ RR؛ نسبت خطر؛ SD؛ ایستادن
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی


- Mortality remains high in immunocompromised patients with acute respiratory failure.
- HFNC was compared with other oxygen techniques for this patient population.
- HFNC significantly improve outcome of ARF in immunocompromised patients.

PurposeAcute respiratory failure remains a common hazardous complication in immunocompromised patients and is associated with increased mortality rates when endotracheal intubation is need. We aimed to evaluate the effect of high-flow nasal cannula oxygen therapy (HFNC) compared with other oxygen technique for this patient population.MethodsWe searched Cochrane library, Embase, PubMed databases before Aug. 15, 2017 for eligible articles. A meta-analysis was performed for measuring short-term mortality (defined as ICU, hospital or 28-days mortality) and intubation rate as the primary outcomes, and length of stay in ICU as the secondary outcome.ResultsWe included seven studies involving 667 patients. Use of HFNC was significantly association with a reduction in short-term mortality (RR 0.66; 95% CI, 0.52 to 0.84, p = 0.0007) and intubation rate (RR 0.76, 95% CI 0.64 to 0.90; p = 0.002). In addition, HFNC did not significant increase length of stay in ICU (MD 0.15 days; 95% CI, − 2.08 to 2.39; p = 0.89).ConclusionsThe results of current meta-analysis suggest that use of HFNC significantly improve outcomes of acute respiratory failure in immunocompromised patients. Owing to the quality of the included studies, further adequately powered randomized controlled trials are needed to confirm our results.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Critical Care - Volume 43, February 2018, Pages 300-305
نویسندگان
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