کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5583512 1567672 2017 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The role of vasopressin and the vasopressin type V1a receptor agonist selepressin in septic shock
ترجمه فارسی عنوان
نقش وازوپرسین و واپرسین نوع واژینال آلفا تیپ واژینال واپرسین در اثر شوک سپتیک
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی بیهوشی و پزشکی درد
چکیده انگلیسی
Septic shock remains one of the major causes of morbidity and mortality in the critically ill. Despite early goal therapy and administration of cathecholaminergic agents, up to 30% of patients succumb to the disease. In this manuscript, we first summarize the standard of care of patients with septic shock and current guidelines. We review the physiologic role of vasopressin and its role in septic shock management. We then review the most up-to-date evidence on the potential role of V1a receptor agonists such as Selepressin, in septic shock. Exciting new trials are being completed in order to elucidate the role of V1a receptor agonists as potential first-line vasopressor alternatives in the therapy of circulatory shock in septic patients.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Critical Care - Volume 40, August 2017, Pages 41-45
نویسندگان
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