KCNQ1 gene polymorphism is associated with glycaemic response to treatment with DPP-4 inhibitors

KCNQ1 rs163184 T > G variant was associated with a reduced glycaemic response to DPP4I. The difference of 0.6% (6.5 mmol/mol) in HbA1c reduction between the TT and GG homozygotes might be of clinical significance if replicated in further studies.