|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5590865||1404721||2017||3 صفحه PDF||سفارش دهید||دانلود کنید|
- This is the second case of Merkel cell carcinoma with the MCPy virus and fingolimod.
- Fingolimod may reactivate latent viruses, such as the Merkel cell polyoma virus.
- Clinicians should seek expert consultation for suspicious skin lesions.
Neoplasms and reactivation of latent viruses have been observed in individuals taking fingolimod. Merkel cell carcinoma (MCC), a rare neuroendocrine skin cancer, is associated with immunosuppression and can be triggered by the oncogenic Merkel cell polyoma virus (MCPyV). We report a case of a 61-year-old man with multiple sclerosis who developed MCPyV-positive MCC 4 years after starting fingolimod. This is the second report of MCC associated with MCPyV in an individual on fingolimod.
Journal: Multiple Sclerosis and Related Disorders - Volume 17, October 2017, Pages 12-14