کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5590867 1570200 2017 3 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله ISI
Case reportA case of lymphoma in a patient on teriflunomide treatment for relapsing multiple sclerosis
ترجمه فارسی عنوان
گزارش موردی مورد لنفوم در بیمار بر درمان تری فلومونید برای عود بیماری های مولتیپل اسکلروزیس
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری بیوشیمی، ژنتیک و زیست شناسی مولکولی ژنتیک
چکیده انگلیسی


- A 54-year-old black woman with MS developed follicular lymphoma after 8 months of therapy with teriflunomide.
- This is the first published case of a patient developing lymphoma while receiving teriflunomide treatment.
- At least 10 more cases have so far been reported to pharmacovigilance worldwide.
- An association between teriflunomide and a higher risk of lymphoma cannot be excluded.

Teriflunomide is an oral therapy approved for relapsing forms of multiple sclerosis which has been shown to reduce relapse rate and disability progression. We report the case of a 54-year -old black woman with multiple sclerosis who developed follicular lymphoma after about 8 months of exposure to teriflunomide. Importantly, apart from age, the patient had none of the established risk factors for follicular lymphoma. Moreover, although this is the first published case of a lymphoma on teriflunomide, it is not the first confirmed case. Ten other cases have so far been reported to pharmacovigilance worldwide, and a further 82 with leflunomide. In conclusion, an association between teriflunomide and a higher risk of lymphoma cannot be ruled out.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Multiple Sclerosis and Related Disorders - Volume 17, October 2017, Pages 92-94
نویسندگان
, , , ,