کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5620438 | 1406103 | 2017 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Fibrosis endomiocárdica
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کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت
پزشکی و دندانپزشکی
کاردیولوژی و پزشکی قلب و عروق
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چکیده انگلیسی
Endomyocardial fibrosis or Löffler endocarditis is a condition whose cause still remains unknown. It can develop during the progress of multiple infectious or tumour diseases, medication, etc. In many cases, showing moderate eosinophilia (more than 1500 eosinophils/microliter) for long periods of time can cause organ toxicity, among them the heart. This produces a dysfunction of the heart due to direct infiltration, which damages the tissue, and also due to the proteins found in the granules, mostly eosinophil cationic protein and major basic protein, which have a predilection for endocardial tissue, leading to their cell destruction, which will translate into a subcardial enlargement and fibrosis. These alterations result in restrictive cardiomyopathy, endomyocardial fibrosis being their main cause. We present the case of a 30 year-old male patient who is admitted at the hospital due to acute heart failure with an admission echocardiogram that evidenced a restrictive biventricular component, present in up to 51% of the cases in different series. The patient had a base hematological disorder, where eosinophilia had been persistent for more than 6 months.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Revista Colombiana de CardiologÃa - Volume 24, Issue 1, JanuaryâFebruary 2017, Pages 59.e1-59.e6
Journal: Revista Colombiana de CardiologÃa - Volume 24, Issue 1, JanuaryâFebruary 2017, Pages 59.e1-59.e6
نویسندگان
Alejandro Villamil-Munévar, Christian Barbosa, Alfonso Ternera-Barrios, Jorge Luis Pinedo, Alejandro Olaya,