|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5630322||1406446||2017||3 صفحه PDF||ندارد||دانلود کنید|
Multiple Sclerosis is a demyelinating disease of the central nervous system (CNS) affecting young individuals with age range of 20â40Â years of age. The precise mechanism underlying the disease is still unclear. Some viruses have been proposed to play roles in disease causation. In this study, we recruited 800 MS patients along with 1000 healthy individuals to determine the seropositivity of anti-CMV and anti-VZV IgG titers using enzyme-linked immunosorbent assay (ELISA). Our results showed significant higher titers of anti-CMV and anti-VZV IgG titers in serum of MS patients with respect to healthy individuals (for both pÂ <Â 0.001). It seems that CMV and VZV play a key role in MS pathogenesis.
Journal: Journal of Neuroimmunology - Volume 309, 15 August 2017, Pages 4-6