کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5630325 | 1580366 | 2017 | 4 صفحه PDF | دانلود رایگان |
- Patient presents with suspected bacterial meningomyelitis
- CSF and blood tests for bacteria, fungi, tuberculosis, antinuclear antibody all negative
- MRI revealed several vertebral transverse and area postrema lesions.
- Test for serum anti-aquaporin-4 antibody is positive.
- Diagnosis may support hypothesis that pathogenesis of NMO triggered by infection.
A rare case of neuromyelitis optica spectrum disorder, suspected to be bacterial meningomyelitis as the initial manifestation, is reported. The patient presented with initial symptoms of meningomyelitis and fever. Cerebrospinal fluid analysis revealed pleocytosis (1280Â ÃÂ 106/L [98% lymphocytes]) and glucose level of 1.8Â mmol/L. Magnetic resonance imaging revealed >Â 3 vertebral, longitudinally extensive transverse myelitis and area postrema lesions. Right optic neuritis was experienced 20Â months after the first attack. Serum anti-aquaporin-4 antibody was positive, and a diagnosis of neuromyelitis optica spectrum disorder was made, supporting the hypothesis that the pathogenesis of neuromyelitis optica is triggered by infection.
Journal: Journal of Neuroimmunology - Volume 309, 15 August 2017, Pages 68-71