|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5650429||1588076||2017||5 صفحه PDF||سفارش دهید||دانلود کنید|
BackgroundThe aim of this study was to investigate whether the 1-year survival rate of out-of-hospital cardiac arrest (OHCA) patients with malignancy was different from that of those without malignancy.MethodsAll adult OHCA patients were retrospectively analyzed in a single institution for 6Â years. The primary outcome was 1-year survival, and secondary outcomes were sustained return of spontaneous circulation (ROSC), survival to hospital admission, survival to discharge and discharge with a good neurological outcome (CPC 1 or 2). Kaplan-Meier survival analysis and Cox proportional hazard regression analysis were performed to test the effect of malignancy.ResultsAmong 341 OHCA patients, 59 patients had malignancy (17.3%). Sustained ROSC, survival to admission, survival to discharge and discharge with a good CPC were not different between the two groups. The 1-year survival rate was lower in patients with malignancy (1.7% vs 11.4%; PÂ =Â 0.026). Kaplan-Meier survival analysis revealed that patients with malignancy had a significantly lower 1-year survival rate when including all patients (nÂ =Â 341; PÂ =Â 0.028), patients with survival to admission (nÂ =Â 172, PÂ =Â 0.002), patients with discharge CPC 1 or 2 (nÂ =Â 18, PÂ =Â 0.010) and patients with discharge CPC 3 or 4 (nÂ =Â 57, PÂ =Â 0.008). Malignancy was an independent risk factor for 1-year mortality in the Cox proportional hazard regression analysis performed in patients with survival to admission and survival to discharge.ConclusionsAlthough survival to admission, survival to discharge and discharge with a good CPC rate were not different, the 1-year survival rate was significantly lower in OHCA patients with malignancy than in those without malignancy.
Journal: The American Journal of Emergency Medicine - Volume 35, Issue 10, October 2017, Pages 1457-1461