|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5662733||1590495||2017||4 صفحه PDF||سفارش دهید||دانلود کنید|
SummaryBackgroundStudies have shown a positive correlation between hospital admission and antimicrobial-resistant bacteria (ARB)-related community-acquired bacteremia (CAB), however, the definition regarding the duration from prior hospitalization as having risks for such infections varies between literatures. Therefore, we conducted a retrospective analysis to determine the time-effect of recent hospitalization on the risk of CAB due to extended-spectrum beta-lactamases (ESBLs)-producing Enterobacteriaceae in elderly patients.MethodsFrom 2006 to 2008, all consecutive episodes of documented bacteremia developed within first 48Â h of hospital admission due to E.Â coli and K.Â pneumoniae in patient age of 65 or greater were retrospectively enrolled.ResultsOut of 494 non-duplicated CAB episodes, 9.5% were due to ESBLs-producing E.Â coli/K. pneumoniae. Age, history of previous hospital admission, and nursing home residents were independently associated with the risk for CAB due to ESBLs-producing E.Â coli/K. pneumoniae. History of previous hospitalization was the most significant one among these risks and the effect was time-dependent: within 2â¼30Â days (OR 8.8; 95% CI 1.9 to 41.2), 31â¼90Â days (OR 9.0; 95% CI 1.9 to 41.2), 91â¼180Â days (OR 5.6; 95% CI 1.1 to 29.1), 181â¼360Â days (OR 5.5; 95% CI 1.0 to 29.1) and over 360Â days (OR 3.5; 95% CI 0.5 to 22.7).ConclusionOur study showed that the risk of CAB in elderly due to ESBLs-producing E.Â coli/K. pneumoniae was highly associated with history of recent hospital admissions, and the effect can be prolonged up to 360Â days after discharge.
Journal: International Journal of Gerontology - Volume 11, Issue 1, March 2017, Pages 27-30