کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5662960 1407600 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Magnitude and determinants of adverse treatment outcomes among tuberculosis patients registered under Revised National Tuberculosis Control Program in a Tuberculosis Unit, Wardha, Central India: A record-based cohort study
ترجمه فارسی عنوان
میزان و عوامل تعیین کننده پیامدهای درمان نامطلوب در میان بیماران سل که تحت برنامه کنترل ملی مبارزه با بیماری سل در یک واحد سل، وردا، هندوستان، ثبت شده است: یک مطالعه همگروه مبتنی بر رکورد
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی انفورماتیک سلامت
چکیده انگلیسی

IntroductionDeaths, defaults, relapses, and treatment failures have made the control of TB difficult across the globe.MethodologyThis study is a record-based follow-up of a cohort of patients registered under Revised National Tuberculosis Control Program in the year 2014 in Wardha Tuberculosis Unit, India. Data was collected from the records available at the District Tuberculosis Office.ResultsData of 510 patients was analyzed. The sputum conversion rate was 88%. The overall treatment success rate was 81.9%, and rates of any adverse outcome, deaths, defaults, failure, and shift to Category IV regimen were 32.60/100 person years at risk (PYAR), 16.88/100 PYAR, 11.12/100 PYAR, 3.45/100 PYAR, and 1.15/100 PYAR, respectively. The median times for the above outcomes were 81 days, 110 days, 66 days, 118 days, and 237 days, respectively. The cumulative probability of occurrence at 6 months of any adverse outcome, deaths, default, failure, and shift to Category IV regimen was 0.145, 0.056, 0.088, 0.002, and 0.004, respectively. On multivariate analysis, the determinant of any adverse outcome was age >45 years, whereas extrapulmonary disease was protective. The hazard of defaulting was also significantly higher in male patients and those aged >45 years.ConclusionAppropriate interventions and program implementation to reduce the adverse treatment outcomes and interruptions will help in improving program performance.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Epidemiology and Global Health - Volume 7, Issue 2, June 2017, Pages 111-118
نویسندگان
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