کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5665795 1407771 2017 8 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Tree-structured survival analysis of patients with Pseudomonas aeruginosa bacteremia: A multicenter observational cohort study
ترجمه فارسی عنوان
تجزیه و تحلیل بقای درختان در بیماران مبتلا به باکتری های پوسیدوموناس آئروژینوزا: یک مطالعه کوهورت مشاهدات چندتایی
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی


- Predictors for mortality were evaluated for patients with P. aeruginosa bacteremia.
- Combination therapy does not render survival benefit in these patients.
- Survival tree analysis is useful for evaluating clinical outcomes in patients.

This study aimed to construct a prediction algorithm, which is readily applicable in the clinical setting, to determine the mortality rate for patients with P. aeruginosa bacteremia. A multicenter observational cohort study was performed retrospectively in seven university-affiliated hospitals in Korea from March 2012 to February 2015. In total, 264 adult patients with monomicrobial P. aeruginosa bacteremia were included in the analyses. Among the predictors independently associated with 30-day mortality in the Cox regression model, Pitt bacteremia score >2 and high-risk source of bacteremia were identified as critical nodes in the tree-structured survival analysis. Particularly, the empirical combination therapy was not associated with any survival benefit in the Cox regression model compared to the empirical monotherapy. This study suggests that determining the infection source and evaluating the clinical severity are critical to predict the clinical outcome in patients with P. aeruginosa bacteremia.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 87, Issue 2, February 2017, Pages 180-187
نویسندگان
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