|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|5665897||1407776||2017||3 صفحه PDF||سفارش دهید||دانلود کنید|
- The in vitro synergy between ceftazidime, aztreonam, and ceftazidime-avibactam was assessed against 7 serine and metallo-Î²-lactamase producing pathogens
- Aztreonam and ceftazidime-avibactam were synergistic against metallo-Î²-lactamase-producing Enterobacteriaceae spp.
- None of the combinations tested were consistently synergistic against IMP-producing Pseudomonas aeruginosa.
- The Etest MIC:MIC ratio method may be clinically practical for assessing synergy.
This study assessed the in vitro synergy between ceftazidime, aztreonam, and ceftazidime-avibactam against serine and metallo-Î²-lactamase (MBL)-producing pathogens via the Etest MIC:MIC ratio and Agar-Etest synergy methods. The combination of aztreonam and ceftazidime-avibactam was synergistic against all Enterobacteriaceae. None of the tested combinations were consistently synergistic against IMP-producing P. aeruginosa.
Journal: Diagnostic Microbiology and Infectious Disease - Volume 88, Issue 4, August 2017, Pages 352-354