کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5665900 1407776 2017 3 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline
کلمات کلیدی
Extended-spectrum beta-lactamase; Multidrug resistance; KPC; Tetracycline; Resistant;
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Activity of minocycline against Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae clinical isolates, with comparison to doxycycline and tigecycline
چکیده انگلیسی

•Previous studies have suggested KPC-producing Enterobacteriaceae may have intermediate susceptibility to tetracyclines•In vitro activity of minocycline was examined for 103 KPC-producing Enterobacteriaceae•Approximately half had susceptible (26%) or intermediate (26%) minocycline MICs•For a subset (n = 35), susceptibility was highest to tigecycline followed by minocycline and then doxycycline

We examined the in vitro activity of minocycline against 103 Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae isolates and found approximately half had susceptible (26%) or intermediate (26%) MICs. For a subset of 35 isolates, susceptibility was highest to tigecycline (71% FDA vs. 20% EUCAST) followed by minocycline (14%) and then doxycycline (6%).

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 88, Issue 4, August 2017, Pages 365-367
نویسندگان
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