کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5665941 1407778 2017 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Hematogenous vertebral osteomyelitis associated with intravascular device-associated infections - A retrospective cohort study
ترجمه فارسی عنوان
استئومیلیت های مهره ای هماتوژن همراه با عفونت های مرتبط با دستگاه عضلانی - مطالعه کوهورت گذشته نگر
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
چکیده انگلیسی


- Hematogenous vertebral osteomyelitis may originate from infected intravascular devices.
- The predominant pathogens in the cohort were coagulase-negative staphylococci.
- Blood cultures revealed the causing pathogen in most patients.

IntroductionAim of the study was to investigate the clinical, microbiological, radiological, and treatment characteristics of hematogenous vertebral osteomyelitis originating from infected intravascular devices.Patients and MethodsPatients with secondary hematogenous vertebral osteomyelitis caused by an infected intravascular device were included in this retrospective cohort study. Patients with prior spinal surgery were excluded. Categorical variables were compared using χ2 or Fisher's exact tests and continuous variables using the Mann-Whitney U test.ResultsSixty-seven patients with hematogenous vertebral osteomyelitis were included. Intravenous catheters were the source of infection in 45 patients (67%) and cardiovascular devices in 22 (33%). Fever was present in 21 patients (45%). The main pathogens were coagulase-negative staphylococci, isolated in 42 patients (63%), which grew from blood culture in 52 patients (87%), from vertebral tissue in 29 patients (56%) and from the explanted intravascular device in 18 patients (60%), where it was sampled. Infective endocarditis was diagnosed in 14 of 45 patients (31%), more common with cardiovascular devices than with intravascular catheters (56% versus 15%; P = 0.008).ConclusionsIn patients with vertebral osteomyelitis, growth of coagulase-negative staphylococci in blood is highly suggestive for intravascular device-associated infection. Despite absence of systemic or local signs of inflammation at the site of the device, blood cultures should be collected and echocardiography performed in these patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 88, Issue 1, May 2017, Pages 75-81
نویسندگان
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