کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5665962 | 1407779 | 2017 | 4 صفحه PDF | دانلود رایگان |
- Resistance antibiotic genes advise a better therapeutic option to patients.
- MDR is conferred by plasmids that can spread to different bacterial groups.
- E. coli B2, ST131, CTX-M-15 producer is the most frequent pathogen causing UTI.
- Sulfamethoxazole-trimethoprim as therapeutic option is no longer effective.
We investigated the molecular characteristics of ESBL-producing E. coli (ESBL-PEc) isolates from two hospitals and community settings in Ciudad Obregon, Sonora, Mexico. Between 2011 and 2014, thirty-seven ESBL-PEc isolates were collected. The major encoded ESBL was the blaCTX-M-15 gene (97%); followed by 13.5% of the blaSHV-12 gene, and 5.5% encoded the blaTLA-1 gene. The PMQR gene aac(6´)-Ib-cr was detected in 97% of the isolates and the qnrB gene, in one isolate. The ESBL-PEc isolates corresponded to phylogenetic group B2, ST131. Our results highlight the dissemination of ESBL-PEc isolates in northwest Mexico (Ciudad Obregon, Sonora).
Journal: Diagnostic Microbiology and Infectious Disease - Volume 87, Issue 1, January 2017, Pages 49-52