کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5665967 1407779 2017 3 صفحه PDF سفارش دهید دانلود کنید
عنوان انگلیسی مقاله
Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
چکیده انگلیسی


- Three hundred twenty-eight E. coli, 35 Klebsiella spp., (1 K. oxytoca and 34 K. pneumoniae) and 16 Enterobacter spp. (1 E. aerogenes and 15 E. cloacae) well-characterized isolates nonsusceptible to third-generation cephalosporins were tested by broth microdilution antimicrobial susceptibility testing.
- The following concentration ranges were included: ampicillin/sulbactam (2/4-16/4 mg/L), amoxicillin/clavulanic acid (4/2-32/2 mg/L), piperacillin/tazobactam (1/4-128/4 mg/L), mecillinam (0.5-64 mg/L), mecillinam/clavulanic acid (0.5/4-64/4 mg/L), and temocillin (1-128 mg/L).
- Our study gives insight in β-lactam MIC distributions of a collection of well-characterized German 3GCREB isolates. Several β-lactam antibiotics showed good in vitro activity and may serve as treatment options for infections.

As part of the multicenter Antibiotic Therapy Optimisation Study-the largest study on the prevalence of third-generation cephalosporin-resistant Enterobacteriaceae carriage upon hospital admission-minimum inhibitory concentration values were generated for ampicillin/sulbactam, amoxicillin/clavulanic acid, piperacillin/tazobactam, mecillinam, mecillinam/clavulanic acid, and temocillin against third-generation cephalosporin-resistant Escherichia coli, Klebsiella species and Enterobacter species.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 87, Issue 1, January 2017, Pages 71-73
نویسندگان
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