کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5665967 1407779 2017 3 صفحه PDF ندارد دانلود کنید
عنوان انگلیسی مقاله
Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
Susceptibility to penicillin derivatives among third-generation cephalosporin-resistant Enterobacteriaceae recovered on hospital admission
چکیده انگلیسی

•Three hundred twenty-eight E. coli, 35 Klebsiella spp., (1 K. oxytoca and 34 K. pneumoniae) and 16 Enterobacter spp. (1 E. aerogenes and 15 E. cloacae) well-characterized isolates nonsusceptible to third-generation cephalosporins were tested by broth microdilution antimicrobial susceptibility testing.•The following concentration ranges were included: ampicillin/sulbactam (2/4–16/4 mg/L), amoxicillin/clavulanic acid (4/2–32/2 mg/L), piperacillin/tazobactam (1/4–128/4 mg/L), mecillinam (0.5–64 mg/L), mecillinam/clavulanic acid (0.5/4–64/4 mg/L), and temocillin (1–128 mg/L).•Our study gives insight in β-lactam MIC distributions of a collection of well-characterized German 3GCREB isolates. Several β-lactam antibiotics showed good in vitro activity and may serve as treatment options for infections.

As part of the multicenter Antibiotic Therapy Optimisation Study—the largest study on the prevalence of third-generation cephalosporin-resistant Enterobacteriaceae carriage upon hospital admission—minimum inhibitory concentration values were generated for ampicillin/sulbactam, amoxicillin/clavulanic acid, piperacillin/tazobactam, mecillinam, mecillinam/clavulanic acid, and temocillin against third-generation cephalosporin-resistant Escherichia coli, Klebsiella species and Enterobacter species.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 87, Issue 1, January 2017, Pages 71-73
نویسندگان
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