کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5665986 1407780 2017 3 صفحه PDF ندارد دانلود کنید
عنوان انگلیسی مقاله
First report of NDM-1-producing clinical isolate of Leclercia adecarboxylata in Spain
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی میکروبیولوژی و بیوتکنولوژی کاربردی
پیش نمایش صفحه اول مقاله
First report of NDM-1-producing clinical isolate of Leclercia adecarboxylata in Spain
چکیده انگلیسی

•First case of NDM-1-producing Leclercia adecarboxylata in Spain and second in the world•The isolate was resistant to beta-lactams, quinolones, trimetroprim-sulfametoxazol, gentamicin and tobramycin.•Plasmid encoding blaNDM-1 belongs to the incompatibility group X3, a described vector for NDM-1 dissemination in China.•Species of uncertain clinical relevance could be vehicles for resistance determinants.

We describe the case of NDM-1-producing Leclercia adecarboxylata recovered from the clinical sample of a patient hospitalized for a trauma-related injury to his foot. The isolate was resistant to all beta-lactams, quinolones, trimetroprim-sulfametoxazol, gentamicin and tobramicyn. The blaNDM-1 gene was located in a conjugative plasmid that also contained the blaSHV-12 gene and was preceded by a disrupted insertion sequence of ISAba125. The plasmid belongs to the incompatibility group X3, which is known to be an important vector for NDM-1 dissemination in China. This is the first reported case of NDM-1 L. adecarboxylata in our country and evidences that species of uncertain clinical relevance can act as hidden sources of clinically important resistance determinants.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Diagnostic Microbiology and Infectious Disease - Volume 88, Issue 3, July 2017, Pages 268-270
نویسندگان
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