کد مقاله کد نشریه سال انتشار مقاله انگلیسی ترجمه فارسی نسخه تمام متن
5670989 1408037 2018 3 صفحه PDF ندارد دانلود رایگان
عنوان انگلیسی مقاله
Therapeutic efficacy of artesunate - amiodaquine for treating uncomplicated falciparum malaria at Ghindae Zonal Referral Hospital, Eritrea
کلمات کلیدی
Plasmodium falciparum; Eritrea; Therapeutic efficacy; ACPR;
موضوعات مرتبط
علوم زیستی و بیوفناوری ایمنی شناسی و میکروب شناسی انگل شناسی
پیش نمایش صفحه اول مقاله
Therapeutic efficacy of artesunate - amiodaquine for treating uncomplicated falciparum malaria at Ghindae Zonal Referral Hospital, Eritrea
چکیده انگلیسی

IntroductionThe aim of this study was to assess the efficacy of artesunate-amodiaquine (AS + AQ) which is the first-line treatment for uncomplicated falciparum malaria in Eritrea.Materials and methodsThe study was conducted from December 2014 to March 2015 in Ghindae Zonal Referral Hospital in Northern Red Sea Zone. Out of 481 patients screened, 103 were enrolled in the study. The therapeutic efficacy test was done as per the WHO protocol for a period of 28 days of follow-up.ResultsThe PCR-uncorrected treatment outcome was classified as adequate clinical and parasitological response (ACPR) in 95 patients, which meant the cure rate was 96.0 (95% CI: 89.7%–98.5%) after survival analysis.ConclusionsTherapeutic efficacy of AS + AQ still meets the WHO efficacy criteria for its continued use in the study area as the first-line drug against uncomplicated falciparum malaria. However, further studies are needed using correction with molecular markers to monitor therapeutic efficacy of antimalarial drugs in this area.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Acta Tropica - Volume 177, January 2018, Pages 94-96
نویسندگان
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