کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5731218 1611466 2017 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Idiopathic granulomatous mastitis: A diagnostic and therapeutic challenge
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی عمل جراحی
پیش نمایش صفحه اول مقاله
Idiopathic granulomatous mastitis: A diagnostic and therapeutic challenge
چکیده انگلیسی


- Idiopathic granulomatous mastitis (IGM) is challenging to treat since the etiology is unclear.
- Those diagnosed with IGM tend to be young, within five years post-partum, and present with a persistent painful mass.
- Excision of the mass is successful in halting the process in approximately 85% of the patients.
- Corticosteroids may conserve breast tissue in patients with a sterile abscess and no contraindications to immunosuppression.

BackgroundIdiopathic granulomatous mastitis is a rare benign breast disease of women of reproductive age. It usually presents as a painful mass. Since the etiology is unclear, directed diagnosis and management is lacking.MethodsThis is a retrospective chart review of 14 patients, over twelve years (2004-2016), identified through query of pathology findings.ResultsTwo asymptomatic patients were diagnosed after oncologic breast resection following neoadjuvant chemotherapy. The remaining twelve patients were young (31.7 years, range 23-43 years), predominantly non-white (50% African/African-American, 36% Hispanic, 7% Asian), pregnant within the last five years (86%), with no prior granulomatous disease. Evaluation included breast imaging, microbial cultures and staining, and biopsy. Treatment included antibiotics (57%), corticosteroids (21%), methotrexate (7%), and/or surgery (71%). Imaging suggests segmental masses, possibly abscess.ConclusionGranulomatous mastitis is uncommon, and difficult to diagnose and manage. We review our experience, the literature, and propose an algorithm for diagnosis and management.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: The American Journal of Surgery - Volume 214, Issue 4, October 2017, Pages 701-706
نویسندگان
, , , , , , , , ,