کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5736182 1613193 2017 13 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
How age, sex and genotype shape the stress response
ترجمه فارسی عنوان
چگونه سن، جنس و ژنوتیپ شکل پاسخ به استرس
کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


- Effect of age in the stress response.
- Effect of sex in the stress response.
- Effect of genotype in the stress response.

Exposure to chronic stress is a leading pre-disposing factor for several neuropsychiatric disorders as it often leads to maladaptive responses. The response to stressful events is heterogeneous, underpinning a wide spectrum of distinct changes amongst stress-exposed individuals'. Several factors can underlie a different perception to stressors and the setting of distinct coping strategies that will lead to individual differences on the susceptibility/resistance to stress. Beyond the factors related to the stressor itself, such as intensity, duration or predictability, there are factors intrinsic to the individuals that are relevant to shape the stress response, such as age, sex and genetics. In this review, we examine the contribution of such intrinsic factors to the modulation of the stress response based on experimental rodent models of response to stress and discuss to what extent that knowledge can be potentially translated to humans.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neurobiology of Stress - Volume 6, February 2017, Pages 44-56
نویسندگان
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