Integrated microarray analysis provided a new insight of the pathogenesis of Parkinson's disease

Several DEGs including SNCA, COX17, COX4I1, COX7B, COX6A1 and ATP5J targeted by Pax-4, Oct-1 and Evi-1 may involve in the neurodegeneration and pathogenesis of PD by regulating oxidative phosphorylation, ATP production and oxidative stress, which was benefit for uncovering the mechanism of PD and developing new diagnostic and therapeutic strategies.