کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5748648 1619143 2017 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Assessment of sublethal endpoints after chronic exposure of the nematode Caenorhabditis elegans to palladium, platinum and rhodium
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم محیط زیست شیمی زیست محیطی
پیش نمایش صفحه اول مقاله
Assessment of sublethal endpoints after chronic exposure of the nematode Caenorhabditis elegans to palladium, platinum and rhodium
چکیده انگلیسی


- Bleaching for age synchronization of Caenorhabditis elegans may enhance test reproducibility and sensitivity.
- PGE toxicity to Caenorhabditis elegans decreased in the following order: Pd > Pt » Rh.
- Pd response pattern showed decreasing effects at the highest exposure concentrations.
- 96 h EC50 values for growth, fertility and reproduction were determined for Pt.

The aim of this study was to investigate chronic effects of the platinum-group elements (PGE) palladium (Pd), platinum (Pt) and rhodium (Rh) on the nematode Caenorhabditis elegans. Aquatic toxicity testing was carried out according to ISO 10872 by determining 96 h EC50 values for sublethal endpoints, including growth, fertility and reproduction. Single PGE standard solutions were used as metal source. Based on the EC50 values for Pt, reproduction (96 h EC50 = 497 μg/L) was the most sensitive endpoint followed by fertility (96 h EC50 = 726 μg/L) and growth (96 h EC50 = 808 μg/L). For Pd, no precise EC50 values could be calculated due to bell-shaped concentration response curves, but the 96 h EC50 for reproduction ranged between 10 and 100 μg/L. Pd and Pt had effects on all endpoints. With raising element concentrations reproduction was inhibited first. At a certain concentration, fertility was also affected, which in turn had an additional effect on reproduction. Growth inhibition can also lead to a loss of fertility if the worms do not reach an appropriate body size to become fertile. Rhodium showed no inhibition of any endpoint between concentrations of 100 to 10,000 μg Rh/L. The results of this study allow the following order of PGE with respect to decreasing toxicity to C. elegans: Pd > Pt » Rh.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Environmental Pollution - Volume 230, November 2017, Pages 31-39
نویسندگان
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