کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
5767988 | 1413211 | 2017 | 9 صفحه PDF | دانلود رایگان |
- Flaxseed oil was encapsulated in nanoemulsions or alginate microgels.
- Delivery systems were passed through mouth, stomach and small intestine stages.
- Flaxseed oil was fully digested in nanoemulsions.
- Flaxseed oil digestion was retarded when encapsulated in microgels.
- Caseinate retarded flaxseed oil digestion in nanoemulsions and microgels.
Carefully designed delivery systems are required to encapsulate and protect omega-3 fatty acids in commercial food and beverage products, but then release them at the required site-of-action within the human gastrointestinal tract (GIT). Previously, we showed that the oxidative stability of flaxseed oil (a plant-based source of omega-3 fatty acids) encapsulated in nanoemulsion droplets or calcium alginate microgels (hydrogel beads) was improved using caseinate as a natural antioxidant. In this study, the impact of caseinate on the digestion of flaxseed oil encapsulated in these delivery systems was investigated using a simulated GIT. The flaxseed oil was incorporated into four delivery systems: nanoemulsions (NE); nanoemulsions mixed with caseinate (NEÂ +Â C); hydrogel beads (HB); and, hydrogel beads containing caseinate (HBÂ +Â C). The gastrointestinal fate of the flaxseed oil droplets depended on delivery system type and the presence of protein. The flaxseed oil in the nanoemulsions (NE and NEÂ +Â C) was rapidly hydrolyzed within the simulated small intestine, with over 76% and 65% of free fatty acids (FFAs) being released in the first 5 minutes, respectively. Conversely, the flaxseed oil in the hydrogel beads (HB and HBÂ +Â C) was digested much more slowly, with only around 37% and 22% being released in the same period. This knowledge may be useful for designing delivery systems to protect omega-3 fatty acids from oxidation in functional foods, while still allowing them to be released in the GIT.
Encapsulation of omega-3 fatty acids in nanoemulsions and microgels: Impact of delivery system type and protein addition on gastrointestinal fate.150
Journal: Food Research International - Volume 100, Part 1, October 2017, Pages 387-395