کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5794844 1110500 2014 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Evaluation of porcine xenograft in collateral ligament reconstruction in beagle dogs
ترجمه فارسی عنوان
ارزیابی جنتامایسین گوسفند در بازسازی لثه های جانبی در سگهای پیاز
موضوعات مرتبط
علوم زیستی و بیوفناوری علوم کشاورزی و بیولوژیک علوم دامی و جانورشناسی
چکیده انگلیسی


- Irradiated porcine xenografts showed no signs of inflammatory reaction.
- Irradiated porcine xenografts showed greater cellular responses and healing properties.
- Irradiated porcine tendons are useful as xenogenic ligament grafts for reconstruction.

This study evaluated the effectiveness of irradiated porcine tendon xenografts for lateral collateral ligament (LCL) reconstruction. Twenty healthy adult beagle dogs underwent LCL reconstruction using irradiated porcine tendons treated with poly-gamma-glutamic acid. Serological and histological assessments were performed to evaluate host immunological response at 3 and 12 months after surgery. The healing and functional integrity of the LCL reconstructions were assessed by mechanical testing and gait analysis. Histological assessment of the porcine xenografts showed gradual host cellular infiltration and graft collagen remodeling during the healing process. Porcine xenografts showed angiogenesis and no signs of inflammatory reaction. Additionally, biomechanical and gait evaluations supported graft functional integration with no differences between normal and porcine xenograft reconstruction at 12 months after surgery. Irradiated porcine xenografts showed greater cellular responses and healing properties in short- and long-term evaluations. Irradiated porcine tendons appear to be useful as xenografts for the reconstruction of damaged ligaments.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 97, Issue 3, December 2014, Pages 605-610
نویسندگان
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