کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
5871420 1142581 2015 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Original articleMeal patterns in healthy adults: Inverse association of eating frequency with subclinical atherosclerosis indexes
ترجمه فارسی عنوان
مقاله اصلی الگوهای رفتاری بزرگسالان سالم: ارتباط معکوس فرکانس خوردن با شاخص های آترواسکلروز زیرقرص
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی مراقبت های ویژه و مراقبتهای ویژه پزشکی
چکیده انگلیسی

SummaryBackground & aimsMeal patterns and their relationship with cardiovascular disease are insufficiently examined with important clinical implications. Our aim was to investigate associations between eating frequency (EF) and early markers of atherosclerosis.MethodsIn this cross-sectional study, we consecutively recruited 164 healthy subjects (46.8 ± 9.3years, 62 men). EF among other dietary parameters and markers of subclinical atherosclerosis, including flow mediated dilatation (FMD), pulse wave velocity (PWV), intima media thickness (IMT) and the presence of plaques in the carotid arteries were evaluated in all volunteers.ResultsEF was positively associated with total energy intake (EI) and a favorable profile in terms of adiposity, glucose tolerance and blood lipids. Subjects with an increased EF (> median), had significantly lower IMT (p = 0.024) and prevalence of plaques (5.3% vs. 21.3%, p = 0.003), as compared to those below median. IMT and the prevalence of plaques were also significantly lower in those with increased EF compared with subjects with low EF belonging to the same group of energy intake (EI) by EI median. By multivariate regression analysis, carotid plaques remained significantly associated with EF (OR: 0.71, 95% CI 0.56-0.89), while IMT also remained significantly associated with EF after adjustment for age and dietary factors (beta: −0.010, 95% CI: −0.020 to −0.0002), but not after adding obesity-related risk factors.ConclusionIncreased EF is associated with lower prevalence of subclinical atherosclerosis in the carotid arteries in apparently healthy individuals. Whether consumption of the same amount of energy in more eating episodes favorably affects cardiovascular risk should be further investigated.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Clinical Nutrition - Volume 34, Issue 2, April 2015, Pages 302-308
نویسندگان
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