کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
591774 1453881 2016 6 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Effects of heat-treatment on surface morphologies, mechanical properties of nanofibrous poly(propylene carbonate) biocomposites and its cell culture
ترجمه فارسی عنوان
اثرات حرارت عملیاتی بر روی مورفولوژی سطوح، خواص مکانیکی بیو کامپوزیت های پلی (کربنات پروپیلن) و کشت سلولی آن
موضوعات مرتبط
مهندسی و علوم پایه مهندسی شیمی شیمی کلوئیدی و سطحی
چکیده انگلیسی


• PPC nanofibers exhibited soft rubber-like features.
• Mechanics of PPC nanofibers were dramatically improved after heat-treatment.
• PPC/PLA composite nanofibers showed topographically peculiar morphologies.
• Biomedical applications as a scaffold tissue engineering.

We report controlled surface morphologies, mechanical properties and cell culture of biomimetic pure poly(propylene carbonate) (PPC) and PPC/poly(lactic acid) (PLA) composite nanofibers prepared by sol–gel electrospinning. Pure PPC nanofibers exhibited soft rubber-like features with lower mechanical properties (elastic modulus ∼59.7 MPa, tensile strength ∼6.2 MPa), while the mechanical properties of as-spun PPC nanofibers were dramatically improved after heat-treatments at 60 °C. Furthermore, the PPC/PLA composite nanofibers exhibited topographically peculiar morphologies (in particular, an embossing-like surface protrusions), probably due to poor miscibility between PPC and PLA. CCK-8 assay results of cultured myoblasts clarified that pure PPC and PPC/PLA composite nanofibers were nontoxic to the cells, which therefore, suggest them to be used in biomedical applications as a scaffold for tissue engineering.

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ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Colloids and Surfaces A: Physicochemical and Engineering Aspects - Volume 492, 5 March 2016, Pages 138–143
نویسندگان
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