ReviewRoles of Chinese herbal medicines in ischemic heart diseases (IHD) by regulating oxidative stress

- Chinese herbal medicine has shown its enormous potential in prevention and treatment of IHD as an effective antioxidant.
- This review summarizes the common Chinese herbal medicines in regulating oxidative stress in IHD.
- This review represents the possible pathways and targets for Chinese herbal medicine in IHD treatment via regulating oxidative stress.

Ischemic heart disease (IHD) basing on atherosclerosis (AS) is known as a top killer for decades. Oxidative stress, representing excessive oxidation and insufficient elimination, has been proved to be a critical molecular mechanism of IHD and accompanying myocardium dysfunction. Therefore, anti-oxidation therapy may be efficient. Chinese herbal medicine, including extractive compounds, decoctions, patent drugs, and injections, has shown its enormous potential in prevention and treatment of IHD as an effective antioxidant in experimental studies. The aim of this review is to highlight recent studies of Chinese herbal medicine in regulating oxidative stress in IHD. These studies represent recent progress of IHD treatment and indicate the possible pathways and target spots of Chinese herbal medicine.