کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6216886 1273740 2015 5 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Protective effect of early placement of nasogastric tube with solid dilator on tissue damage and stricture formation after caustic esophageal burns in rabbits
ترجمه فارسی عنوان
اثر محافظتی قرار دادن زودهنگام لوله نازا گاستریک با رقیق کننده جامد بر آسیب و ایجاد استریکوبی بافتی پس از سوختگی مریی سوزنی در خرگوش
کلمات کلیدی
مری سوزاننده می سوزد، لوله نازوگاستر، آسیب شناسی، خرگوش،
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی پریناتولوژی (پزشکی مادر و جنین)، طب اطفال و بهداشت کودک
چکیده انگلیسی

BackgroundThe ingestion of caustic substances remains an important public health issue worldwide. Children represent 80% of the ingestion injury population globally. Accidental alkaline material accounts for most caustic ingestions. There is no conclusive evidence of tissue damage and stricture protection of a nasogastric-tube with a solid dilator in the literature, therefore it was hypothesized that early intraesophageal tube placement does not cause additional histopathologic damage and prevents strictures.MethodsAn exploratory study on experimental caustic esophageal burns in a rabbit model was designed. In the treated group a silicone tube was placed immediately after causing the burns, while the untreated group followed the natural course of the burn. On the twenty-second day, an esophagectomy was performed on all animals for microscopic (Histopathologic Damage Score and Stenosis Index) and macroscopic analysis.ResultsForty animals were randomly divided into two groups. The Histopathologic Damage Score was 3.7 ± 1.1 in the treated group versus 3.9 ± 1.2 in the untreated group (p = .9690). The Stenosis Index was 0.6 ± 0.1 in treated rabbits versus 2.3 ± 0.2 in untreated (p < .0001).ConclusionThe early placement of an intraesophageal tube with solid dilator prevents stenosis formation and does not produce greater tissue damage.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Pediatric Surgery - Volume 50, Issue 8, August 2015, Pages 1264-1268
نویسندگان
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