کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
6230872 1608136 2016 7 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Associations between serum lipid levels and suicidal ideation among Korean older people
ترجمه فارسی عنوان
ارتباط بین سطوح چربی سرم و ایده های خودکشی در میان افراد مسن تر کره ای
کلمات کلیدی
موضوعات مرتبط
علوم پزشکی و سلامت پزشکی و دندانپزشکی روانپزشکی و بهداشت روانی
چکیده انگلیسی


- Lower triglyceride levels were associated with reduced suicidal ideation in elders.
- The association was significant only in men but not in women.
- Gender specific mechanisms in lipid levels and suicidality can be suggested.
- The role of lipid levels on suicidality may be different in old age population.

IntroductionThere have been inconsistent reports on the relationships between lipids and suicidality, and studies conducted in older adults are rare. This study examined associations between serum lipid levels and suicidal ideation in an older population.MethodsThis study used data obtained from a representative Korean sample of 4265 people age 65 years or older who completed a self-administered questionnaire about suicidal ideation over the last year. The fasting serum concentrations of total cholesterol, high-density lipoprotein cholesterol, low-density lipoprotein cholesterol, and triglycerides were measured and categorized into lower, intermediate (reference), and upper quartiles. A complex sample logistic regression stratified by gender was performed to determine the associations between serum lipid levels and suicidal ideation after controlling for covariates including age, education, marital status, current smoking, alcohol drinking, body mass index, hypertension, diabetes, diagnosed depression, antidepressant use, and lipid-lowering therapies.ResultsIn this study, the prevalence of suicidal ideation in an older Korean population was 22.9% (SE=0.9%). The prevalence was significantly higher in women than in men, 27.7% (1.2%) vs. 15.9% (1.1%) respectively. After adjusting for covariates, lower triglyceride levels were significantly associated with a decreased risk of suicidal ideation (OR=0.65; 95% CI=0.43-0.99) among men but no significant associations were observed among women. Additionally, there were no significant associations between any other measure of cholesterol levels and suicidal ideation in either men or women.LimitationsCross-sectional design cannot infer temporality or the effects of changes in variables.ConclusionsThese results support the association between lower triglyceride levels and a reduced risk of suicidal ideation among Korean men over 65. Further studies are necessary to investigate gender difference and the biological mechanism.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Journal of Affective Disorders - Volume 189, 1 January 2016, Pages 192-198
نویسندگان
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