Pathological changes in acute experimental toxoplasmosis with Toxoplasma gondii strains obtained from human cases of congenital disease

- We conducted a pathological study using mice as a model of T. gondii infection.
- The strains used were obtained from children congenitally infected in Brazil.
- The strains induced similar tissue damage, although genetically diverse.
- Histological changes in the small intestine seem to be dependent on the strain.