|کد مقاله||کد نشریه||سال انتشار||مقاله انگلیسی||ترجمه فارسی||نسخه تمام متن|
|6463110||1422470||2017||3 صفحه PDF||سفارش دهید||دانلود کنید|
- Seven Amerindian groups and two Mestizo (admixed) populations from Mexico were studied.
- Allele frequencies and forensic parameters of the ArgusX-12 kit were estimated.
- Hardy-Weinberg equilibrium was observed in practically all loci/populations.
- Genetic relationships and population structure was evaluated.
- Historical records and X-linked inheritance pattern support the observed population structure.
Allele frequency distribution and statistical parameters of forensic efficiency concerning the Investigator Argus X-12 kit (Qiagen, Hilden, Germany) were determined in a total sample of 641 unrelated Mexican females, including two Mestizo-admixed- populations (nÂ =Â 309) and seven Amerindian groups (nÂ =Â 332) from the main regions of the country. Most of the 12 X-STRs were in agreement with Hardy-Weinberg expectations in all nine Mexican populations. The power of discrimination in females (PD) and Median exclusion chance for trios (MECT) and duos (MECD) of this genetic system based on X-STRs were >99.99%. Although Mexican populations showed significant pairwise differentiation, a closer relationship was evident between Amerindian groups and nearby Mestizos, in agreement with historical records, previous genetic studies, and X-linked inheritance pattern expectations.
Journal: Legal Medicine - Volume 26, May 2017, Pages 62-64