کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
7195952 1468281 2018 11 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Development of multi-walled carbon nanotubes modified pencil graphite electrode for the electrochemical investigation of aceclofenac present in pharmaceutical and biological samples
ترجمه فارسی عنوان
توسعه الکترودهای گرافیت مداد اصلاح شده برای نانولوله های کربنی چندسانی برای بررسی الکتروشیمیایی آکلوفناک در نمونه های دارویی و بیولوژیکی
موضوعات مرتبط
مهندسی و علوم پایه شیمی شیمی آنالیزی یا شیمی تجزیه
چکیده انگلیسی
A sensitive and novel chemically modified multi-walled carbon nanotubes modified pencil graphite electrode (MCPGE) has been developed for the electrochemical investigation of aceclofenac (ACF). MCPGE was characterized by scanning electron microscopy (SEM), cyclic voltammetry (CV) and electrochemical impedance spectroscopy (EIS). Phosphate buffer solution (PBS) of pH 7.0 was used as a suitable electrolytic medium, in which aceclofenac (ACF) exhibited a sensitive adsorption controlled oxidation peaks at + 0.12, + 0.32 and + 0.51 V and a reduction peak at − 0.26 V (vs Ag/AgCl). The experimental conditions were optimised by means of investigating the dependence of peak current on solution pH, concentration and scan rate etc. The electrochemical parameters such as surface concentration (Γ), electron transfer coefficient (α) and the standard rate constant (ks) were investigated at MCPGE. The oxidative peak currents were varied linearly with concentration in the range between 1 × 10− 6 to 60 × 10− 6 M with a detection limit of 2.6 × 10− 9 M. The UV-Vis absorption spectrum of ACF gave the λmax at 272-273 nm and is attributed to the presence of ACF. The applicability of the MCPGE was illustrated by the determination of ACF present in pharmaceutical and human urine samples.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Sensing and Bio-Sensing Research - Volume 17, February 2018, Pages 7-17
نویسندگان
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