Comparative assessment of metal-specific adipogenic activity in zinc and vanadium-citrates through associated gene expression

Well-defined binary Zn(II)/V(IV)-citrate species rise atoxic and efficient toward adipocyte differentiation-maturation. Their capacity to induce cell transformation is exemplified through a common metal-bound citrate ligand, allowing comparative assessment of their adipogenic potential. Complete biochemical profiling projects metallogenetic interactions, rationalizing molecular factors into metallodrug development toward insulin resistance and Diabetes mellitus.115