Specialized metabolites from Ageratina adenophora and their inhibitory activities against pathogenic fungi

Ageratina adenophora is a notorious invasive plant worldwide and has caused great economically loss in southwest China. The specialized metabolites synthesized by this plant may play a role during its invasion. Ten compounds including five previously undescribed ones were isolated and identified from roots of invasive plants A. adenophora. The most abundant compound we isolated in A. adenophora roots was 7-hydroxy-dehydrotremetone, which showed significant broad-spectral inhibitory activity against the growth of all tested fungal strains. 7-hydroxy-dehydrotremetone may act as antifungal metabolite during the invasion of A. adenophora, which may influence the dominance of A. adenophora.108