کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8262205 | 1534834 | 2018 | 5 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Depressive symptoms and muscle weakness: A two-way relation?
ترجمه فارسی عنوان
علائم افسردگی و ضعف عضلانی: رابطه دو طرفه؟
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موضوعات مرتبط
علوم زیستی و بیوفناوری
بیوشیمی، ژنتیک و زیست شناسی مولکولی
سالمندی
چکیده انگلیسی
The potential association between depressive symptoms and dynapenia - i.e. muscle weakness - is limited to few, mainly cross-sectional, studies. We use SHARE (Survey on Health, Ageing and Retirement in Europe) panel data to investigate whether the onset of dynapenia at 4-year follow-up can be explained by pre-existing (either at baseline, or at 2-year follow-up) depressive symptoms, or vice versa. Depressive symptoms were identified as a score of 4 or more on the 12-item EURO-D scale. Individuals were classified as affected by dynapenia if they had handgrip strength of <20â¯kg for women and 30â¯kg for men. We estimate whether being affected by symptoms of depression at baseline or becoming symptomatic between baseline and a 2-year follow-up increases the odds-ratio (OR) for dynapenia at a 4-year follow-up among individuals with no muscle strength impairment at baseline. We also carry out the reverse analysis, and study whether dynapenia at baseline or incident dynapenia between baseline and first follow-up increase the probability that individuals develop depressive symptoms by the second follow-up. The analysis was carried out using multivariate logistic regression. After adjusting for a full set of potential confounders, being symptomatic for depression at baseline did not increase the risk of dynapenia at the 4-year follow-up. Instead, individuals developing depressive symptoms between baseline and the 2-year follow-up had a 34% increased risk of developing dynapenia at the 4-year follow-up (OR 1.34, 95% CI 1.02 1.66). No significant association was detected between dynapenia at baseline or the onset of dynapenia between baseline and the 2-year follow-up and the incidence of depressive symptoms at the 4-year follow-up. In conclusion, our results support the effect of the onset of depressive symptoms on the onset of dynapenia, even after considering the role of confounding factors.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Experimental Gerontology - Volume 108, 15 July 2018, Pages 87-91
Journal: Experimental Gerontology - Volume 108, 15 July 2018, Pages 87-91
نویسندگان
Marco Bertoni, Stefania Maggi, Enzo Manzato, Nicola Veronese, Guglielmo Weber,