کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8503867 | 1554292 | 2018 | 6 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Exploring the oxidative, antimicrobial and genomic properties of Campylobacter jejuni strains isolated from poultry
ترجمه فارسی عنوان
بررسی خواص اکسیداتیو، ضد میکروبی و ژنومی گونه های کمپیلوباکتر ججونی جدا شده از مرغ
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کلمات کلیدی
gDNARNDDNPHTHT6SS2,4-Dinitrophenol - 2،4-دینیتروفنلgenomic DNA - DNA ژنومیBlood agar - آگار خونOxidative stress - تنش اکسیداتیوSensitive - حساسRifampicin - ریفامپینType VI secretion system - سیستم ترشحی VI نوعconfidence intervals - فاصله اطمینانResistant - مقاومAntimicrobial resistance - مقاومت ضد میکروبیresistance-nodulation-division - مقاومت-تخریب-تقسیمhelix-turn-helix - هلیکس به نوبه خود اسپریCampylobacter jejuni - کامپیلوباکتر ژژونیRif - کد عکس
موضوعات مرتبط
علوم زیستی و بیوفناوری
علوم کشاورزی و بیولوژیک
علوم دامی و جانورشناسی
چکیده انگلیسی
Campylobacter jejuni is the leading cause of food-borne bacterial enteritis in humans, with contaminated poultry products considered the main source of infection. To survive the food chain, C. jejuni utilizes multiple defense mechanisms that counter oxidative and aerobic stresses. In this study, we phenotypically characterised 63 C. jejuni strains with oxidative stress survival and antimicrobial susceptibility testing to investigate correlations between these two phenotypes against the source of the strains and the presence of the MarR regulators RrpA and RrpB which have a role in regulating the response to oxidative and aerobic stress. C. jejuni strains isolated from meat and neck skin displayed the highest resistance to oxidative stress. In addition, C. jejuni strains that have an rrpA+rrpBâ profile exhibit increased resistance to oxidative stress and to antimicrobials. Here we establish a preliminary link between the distribution of RrpA and RrpB and the increased resistance to antimicrobials. This study provides insight into how the genotypic make up of C. jejuni can influence the ability of the bacterium to survive within areas of high oxygen stress, such as the food chain, and subsequently can have a potential negative impact on human health.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Research in Veterinary Science - Volume 119, August 2018, Pages 170-175
Journal: Research in Veterinary Science - Volume 119, August 2018, Pages 170-175
نویسندگان
Maria Ugarte-Ruiz, Lucas DomÃnguez, Nicolae Corcionivoschi, Brendan W. Wren, Nick Dorrell, Ozan Gundogdu,