کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8750188 | 1593754 | 2018 | 17 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
Accurate differentiation of Escherichia coli and Shigella serogroups: challenges and strategies
ترجمه فارسی عنوان
تمایز دقیق از گروه های اشرشیا کولی و شیمگل: چالش ها و استراتژی ها
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کلمات کلیدی
موضوعات مرتبط
علوم زیستی و بیوفناوری
ایمنی شناسی و میکروب شناسی
میکروب شناسی
چکیده انگلیسی
Shigella spp. and Escherichia coli are closely related; both belong to the family Enterobacteriaceae. Phenotypically, Shigella spp. and E. coli share many common characteristics, yet they have separate entities in epidemiology and clinical disease, which poses a diagnostic challenge. We collated information for the best possible approach to differentiate clinically relevant E. coli from Shigella spp. We found that a molecular approach is required for confirmation. High discriminatory potential is seen with whole genome sequencing analysed for k-mers and single nucleotide polymorphism. Among these, identification using single nucleotide polymorphism is easy to perform and analyse, and it thus appears more promising. Among the nonmolecular methods, matrix-assisted desorption ionization-time of flight mass spectrometry may be applicable when data analysis is assisted with advanced analytic tools.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: New Microbes and New Infections - Volume 21, January 2018, Pages 58-62
Journal: New Microbes and New Infections - Volume 21, January 2018, Pages 58-62
نویسندگان
N.K. Devanga Ragupathi, D.P. Muthuirulandi Sethuvel, F.Y. Inbanathan, B. Veeraraghavan,