کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
8842126 1615257 2018 33 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
The roles of cortical astrocytes in chronic pain and other brain pathologies
ترجمه فارسی عنوان
نقش آستروسیت های قارچی در درد مزمن و سایر آسیب های مغزی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب (عمومی)
چکیده انگلیسی
Astrocytes are the most abundant cell type in the brain. Several decades ago, they were considered to be only support cells in the central nervous system. Recent studies using advanced technologies have clarified that astrocytes play more active roles in regulating neuronal function and remodeling synaptic structures by releasing molecules called gliotransmitters. In addition to various physiological functions, astrocytes are activated under disease conditions, such as chronic pain, releasing molecules that in turn cause reorganization of the central nervous system microstructure and disrupt behavior in pathological conditions. In the present review, we summarize cortical astrocyte function in chronic pain and other neurological disorders and discuss the role of astrocytes in brain pathologies.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Neuroscience Research - Volume 126, January 2018, Pages 3-8
نویسندگان
, , , ,