کد مقاله | کد نشریه | سال انتشار | مقاله انگلیسی | نسخه تمام متن |
---|---|---|---|---|
8918973 | 1642864 | 2018 | 9 صفحه PDF | دانلود رایگان |
عنوان انگلیسی مقاله ISI
New developments in mechanotransduction: Cross talk of the Wnt, TGF-β and Notch signalling pathways in reaction to shear stress
دانلود مقاله + سفارش ترجمه
دانلود مقاله ISI انگلیسی
رایگان برای ایرانیان
کلمات کلیدی
موضوعات مرتبط
مهندسی و علوم پایه
سایر رشته های مهندسی
مهندسی پزشکی
پیش نمایش صفحه اول مقاله
چکیده انگلیسی
Mechanotransduction, the ability of cells to detect and react to mechanical forces, is increasingly playing a critical role in a variety of physiological and pathophysiological processes. While the focus has previously been on the MAPK, NF-ϰB and ROS generating pathways, ancient embryological pathways have reached little attention. Recently, a surge of new studies have been published on these pathways and their role in mechanotransduction and this review paper aims to provide a concise overview on the latest studies and brings them in to a larger perspective. Special emphasis is on the non-canonical aspects of the Wnt, TGF-β and Notch pathways and their role in flow.
ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: Current Opinion in Biomedical Engineering - Volume 5, March 2018, Pages 96-104
Journal: Current Opinion in Biomedical Engineering - Volume 5, March 2018, Pages 96-104
نویسندگان
Aliah Abuammah, Nataly Maimari, Leila Towhidi, Jenny Frueh, Kok Yean Chooi, Christina Warboys, Rob Krams,