کد مقاله کد نشریه سال انتشار مقاله انگلیسی نسخه تمام متن
930768 1474397 2016 9 صفحه PDF دانلود رایگان
عنوان انگلیسی مقاله ISI
Motivational engagement in Parkinson's disease: Preparation for motivated action
ترجمه فارسی عنوان
مشارکت انگیزشی در بیماری پارکینسون: آمادگی برای عمل انگیزه
کلمات کلیدی
CNV؛ پارکینسون؛ LPP؛ انگیزه؛ تشویق؛ آماده سازی حرکتی
موضوعات مرتبط
علوم زیستی و بیوفناوری علم عصب شناسی علوم اعصاب رفتاری
چکیده انگلیسی


• Examined effect of incentive on action preparation in Parkinson patients
• Measured CNV during action preparation; LPP measured during emotional perception
• Patients showed generally reduced motor preparation, regardless of incentive.
• Patients showed similar effect of incentive on motor preparation as controls.
• Patients and controls show distinct patterns of LPP modulation.

The current study investigated whether motivational dysfunction in Parkinson's patients is related to a deficit in preparing for motivated behavior. Based on previous studies, it was hypothesized that PD patients would show reduced preparation for action specifically when faced with threat (of loss) and that reduced action preparation would relate to self-report of apathy symptoms. The study measured an electrocortical correlate of preparation for action (CNV amplitude) in PD patients and healthy controls, as well as defensive and appetitive activation during emotional perception (LPP amplitude). The sample included 18 non-demented PD patients (tested on dopaminergic medications) and 15 healthy controls who responded as quickly as possible to cues signaling threat of loss or reward, in which the speed of the response determined the outcome. Results indicated that, whereas PD patients showed similar enhanced action preparation with the addition of incentives to controls, PD patients showed generally reduced action preparation, evidenced by reduced CNV amplitude overall. Results suggest that PD patients may have behavioral issues due to globally impaired action preparation but that this deficit is not emotion-specific, and movement preparation may be aided by incentive in PD patients.

ناشر
Database: Elsevier - ScienceDirect (ساینس دایرکت)
Journal: International Journal of Psychophysiology - Volume 99, January 2016, Pages 24–32
نویسندگان
, , , ,