Keywords: DHA; dihydroartemisinin; DMAP; 4-(dimethylamino)-pyridine; DCC; N,Nâ²-dicyclohexylcarbodiimide; DIAD; diisopropyl azodicarboxylate; EC50; half maximal effective concentration; EtOAc; ethylacetate; eq; equivalent; HCMV; human cytomegalovirus; TMSOTf; trim
مقالات ISI (ترجمه نشده)
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Keywords: PfPMT; phosphoethanolamine methyltransferase; UPS; uUbiquitin proteasome system; ART; artemisinin; ACT; artemisinin-based combination therapy; FDA; food and drug administration; DHA; dihydroartemisinin;
Keywords: Dihydroartemisinin; Dipstick; Malaria; Antibody; Immunoassay;
Keywords: Anticancer; Artemisnin; Coumarin; Hybrid; Apoptosis; Ferroptosis; DHA; Dihydroartemisinin; Carbonic anhydrases; CA; Acetazolamide; AAZ; doxorubicin; DOX;
Keywords: Artemisinin; Arteether; Artemether; Artesunate; Dihydroartemisinin; OZ78; OZ401; OZ455; MT04; MT14; Artemisinin and its derivatives; Helminthic infections; Nematodes; Cestodes; Trematodes; Monogenea parasites;
Keywords: ART; artemisinin; b.i.d.; two times per day; CH2CL2; dichloromethane; CI; cell index; DART; dehydroartemisinin; Deoxy-ATS; deoxygenated artesunate; Deoxy-DHA; deoxydihydroartemisinin; DHA; dihydroartemisinin; DMSO; dimethyl sulphoxide; HFF; human foreskin
Keywords: Dihydroartemisinin; Drug conjugates; Cell cycle; Apoptosis; Metastasis; Ovarian cancer;
Keywords: Dihydroartemisinin; Solid lipid nanoparticles; Nanomedicine drug delivery;
Keywords: Malaria; Antitumor; Plasmodium falciparum; Dihydroartemisinin; Chalcone
Keywords: Resistant malaria; Substituted polyphosphazenes; Primaquine; Dihydroartemisinin; Nanoparticles
Keywords: Artemisinin; Dihydroartemisinin; Fluoroquinolone; Antitubercular activity; Antibacterial activity
Keywords: Dihydroartemisinin; Artesunate; Infection; Cancer; Autoimmune disorder; AllergyBcl-2, B-cell lymphoma 2; CMV, cytomegalovirus; CDK, cyclin-dependent kinase; DHA, dihydroartemisinin; dsDNA, double-stranded DNA; HBV, hepatitis B virus; HIF-1α, hypoxia-induc
Keywords: Dihydroartemisinin; COX-2; NF-κB; C/EBP; AP-1; CREB;
Keywords: ART; artemisinin; ARS; artesunate; AD; artemisinin derivative; DHA; dihydroartemisinin; Chemotherapy; HBV; HCV; Hepatoblastoma; Hepatocarcinoma;
Keywords: Dihydroartemisinin; Neuroblastoma cells; Cyclin D1; Caspase-3
Comparison of in vitro/in vivo blood distribution and pharmacokinetics of artemisinin, artemether and dihydroartemisinin in rats
Keywords: Blood distribution; Artemisinin; Artemether; Dihydroartemisinin; LC-MS/MS; Pharmacokinetics;
Dihydroartemisinin ameliorates sepsis-induced hyperpermeability of glomerular endothelium via up-regulation of occludin expression
Keywords: DHA; dihydroartemisinin; AKI; acute kidney injury; LPS; lipopolysaccharide; UACR; urine albumin creatinine ratio; HRGECs; human renal glomerular endothelial cells; TNF-α; tumor necrosis factor-α; VE-cadherin; vascular endothelial cadherin; TGF-β; trans
Dihydroartemisinin induced caspase-dependent apoptosis through inhibiting the specificity protein 1 pathway in hepatocellular carcinoma SK-Hep-1 cells
Keywords: Dihydroartemisinin; Sp1; Caspase; Apoptosis; SK-Hep-1 cells;
Dihydroartemisinin suppresses STAT3 signaling and Mcl-1 and Survivin expression to potentiate ABT-263-induced apoptosis in Non-small Cell Lung Cancer cells harboring EGFR or RAS mutation
Keywords: Dihydroartemisinin; ABT-263; STAT3; Mcl-1; Survivin; Bim;
Dihydroartemisinin alleviates oxidative stress in bleomycin-induced pulmonary fibrosis
Keywords: Dihydroartemisinin; Oxidative stress; Bleomycin; Pulmonary fibrosis;
Dihydroartemisinin inhibits colon cancer cell viability by inducing apoptosis through up-regulation of PPARγ expression
Keywords: Dihydroartemisinin; Apoptosis; Condensation; Matrix metalloprotein; Viability;
Artemisia annua dried leaf tablets treated malaria resistant to ACT and i.v. artesunate: Case reports
Keywords: Artemisinin drug resistance; Artemisia annua; Coartem; ACT; Dihydroartemisinin; Synergism; ACT; Artemisinin combination therapy; AL; Artemether-lumefantrine; DLA; Dried leaf Artemisia annua; i.v.; Intravenous; tr; Trophozoites;
Dihydroartemisinin protects against alcoholic liver injury through alleviating hepatocyte steatosis in a farnesoid X receptor-dependent manner
Keywords: ALD; alcoholic liver disease; ALP; alkaline phosphatase; ALT; alanine aminotransferase; AST; aspartate aminotransferase; BSEP; bile salt export pump; CPT1; carnitine palmitoyltransferase I; CYP7A1; cholesterol 7-alpha hydroxy-lase; DHA; dihydroartemisinin
Dihydroartemisin inhibits glioma invasiveness via a ROS to P53 to β-catenin signaling
Keywords: ChIP; chromatin immunoprecipitation; CKIα; casein kinase Iα; CNS; central nervous system; DHA; dihydroartemisinin; ECM; extracellular matrix; EGFR; epidermal growth factor receptor; ERK1/2; extracellular signal-regulated kinase1/2; GBM; glioblastoma mul
Recent advances of controlled drug delivery using microfluidic platforms
Keywords: AB; Amlodipine besylate; AsnB; Asparaginase B; Ag@CD NPs; Beta-cyclodextrin-coated silver NPs; BSA; Bovine serum albumin; BHCl; Bupivacaine hydrochloride; CTB; Cholera toxin B; CMNs; Coated microneedles; CpG OND; CpG oligonucleotide; DC; Dendritic cell; D
New orally active diphenylmethyl-based ester analogues of dihydroartemisinin: Synthesis and antimalarial assessment against multidrug-resistant Plasmodium yoelii nigeriensis in mice
Keywords: Dihydroartemisinin; Arteether; Antimalarial; Multi-drug resistant; 1,2,4-Trioxanes
Dihydroartemisinin alleviates bile duct ligation-induced liver fibrosis and hepatic stellate cell activation by interfering with the PDGF-βR/ERK signaling pathway
Keywords: Dihydroartemisinin; Liver fibrosis; Hepatic stellate cell; Platelet-derived growth factor β receptor; ERK
Research ArticleArtesunate induces ROS-dependent apoptosis via a Bax-mediated intrinsic pathway in Huh-7 and Hep3B cells
Keywords: ARS; artesunate; ART; artemisinin; ARTs; ART compounds; BSO; l-buthionine-sulfoximine; CCK-8; Cell Counting Kit-8; Cyt.c; cytochrome c; DCF-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; FITC; fluorescein isothiocyanate; FCM;
Artemisinin anti-malarial drugs in China
Keywords: Antimalarials; Artemisinin; Artemether; Artesunate; Dihydroartemisinin
Mechanism of dihydroartemisinin-induced apoptosis in prostate cancer PC3 cells: An iTRAQ-based proteomic analysis
Keywords: Dihydroartemisinin; Prostate cancer; Apoptosis; HSP70; iTRAQ; Proteomics
ROS-JNK1/2-dependent activation of autophagy is required for the induction of anti-inflammatory effect of dihydroartemisinin in liver fibrosis
Keywords: ALT; alanine aminotransferase; AST; aspartate aminotransferase; ALP; alkaline phosphatase; Atg; autophagy-related gene; α-SMA; alpha smooth muscle actin; Cat; catalase; DHA; dihydroartemisinin; ERK1/2; extracellular regulated kinase1/2; GSH; glutathione;
Application of an LC–MS/MS method for reliable determination of amodiaquine, N-desethylamodiaquine, artesunate and dihydroartemisinin in human plasma for a bioequivalence study in healthy Indian subjects
Keywords: Amodiaquine; N-desethylamodiaquine; Artesunate; Dihydroartemisinin; LC–MS/MS; Human plasma
Dihydroartemisinin (DHA) induces ferroptosis and causes cell cycle arrest in head and neck carcinoma cells
Keywords: Head and neck cancer; Dihydroartemisinin; Ferroptosis; Antitumor; Cell cycle; ART; artemisinin; BAX; Bcl-2-associated X protein; Bcl-2; B-cell lymphoma 2; CDC2; cell division cycle protein 2 (also known as cyclin-dependent kinase 1); DFO; deferoxamine; DH
A Randomised, Double Blind, Placebo-Controlled Pilot Study of Oral Artesunate Therapy for Colorectal Cancer
Keywords: Colorectal cancer; Artesunate; Dihydroartemisinin; Ki67; Neutropaenia
Dihydroartemisinin and transferrin dual-dressed nano-graphene oxide for a pH-triggered chemotherapy
Keywords: Dihydroartemisinin; Reactive oxygen species; Graphene oxide; Transferrin; Chemotherapy;
Synthesis and synergetic anti-tumor activity evaluation of dihydroartemisinin-organogermanium(IV) compound
Keywords: Dihydroartemisinin; Ge-132; Organogermanium; Synergetic anti-tumor activity
Refrigeration provides a simple means to synchronize in vitro cultures of Plasmodium falciparum
Keywords: DHA; dihydroartemisinin; PPQ; piperaquine; CQ; chloroquine; QN; quinine; Synchronization; Plasmodium falciparum; Refrigeration; Drug susceptibility;
Dihydroartemisinin potentiates the anticancer effect of cisplatin via mTOR inhibition in cisplatin-resistant ovarian cancer cells: involvement of apoptosis and autophagy
Keywords: Dihydroartemisinin; Cisplatin; Apoptosis; Autophagy; mTOR; Ovarian cancer;
Dihydroartemisinin inhibits activation of the Toll-like receptor 4 signaling pathway and production of type I interferon in spleen cells from lupus-prone MRL/lpr mice
Keywords: Dihydroartemisinin; Lupus; Spleen cells; LPS; TLR4
Dihydroartemisinin induces autophagy by suppressing NF-κB activation
Keywords: DHA; dihydroartemisinin; NF-κB; nuclear factor-kappa B; IκB; inhibitory subunit of NF-κB; TNF-α; tumor necrosis factor-α; AVOs; acidic vesicular organelles; FHC; ferritin heavy chain; MnSOD; manganese superoxide dismutase; ROS; reactive oxygen specie
DJ-1 mediates the resistance of cancer cells to dihydroartemisinin through reactive oxygen species removal
Keywords: ARTs; artemisinin and its derivatives; BCRP; breast cancer resistance protein; DCF-DA; 2â²,7â²-dichlorodihydrofluorescein diacetate; DHA; dihydroartemisinin; DHE; dihydroethidine; 5-FU; 5-fluorouracil; GCLC; glutamate-cysteine ligase catalytic subunit
Monoelectronic reduction of dihydroartemsisinin (DHA): pH dependence and product analysis
Keywords: Dihydroartemisinin; Malaria; γ-Radiolysis; Reduction; Alkoxyl radicals;
LC-MS/MS method for the simultaneous quantitation of three active components derived from a novel prodrug against schistosome infection
Keywords: ARS; artesunate; DHA; dihydroartemisinin; ATM; artemether; PZQ; praziquantel; 10-OHPZQ; 10-hydroxypraziquantel; Prodrug; Artesunate; Dihydroartemisinin; 10-Hydroxypraziquantel; Pharmacokinetics;
Ternary system of dihydroartemisinin with hydroxypropyl-β-cyclodextrin and lecithin: Simultaneous enhancement of drug solubility and stability in aqueous solutions
Keywords: Dihydroartemisinin; Hydroxypropyl-β-cyclodextrin; Ternary system; Solubility; Stability;
Enhancement effect of dihydroartemisinin on human γδ T cell proliferation and killing pancreatic cancer cells
Keywords: γδ T cell; Dihydroartemisinin; Pancreatic cancer; Proliferation; Antitumor activity;
DHA regulates angiogenesis and improves the efficiency of CDDP for the treatment of lung carcinoma
Keywords: DHA; dihydroartemisinin; CDDP; cisplatin; HIF-1α; hypoxia-inducible factor-1 alpha; VEGF; vascular endothelial growth factor; NSCLC; non-small cell lung cancer; DMSO; dimethyl sulfoxide; MTT; 3-(4, 5-dimethylthiazol-2-yl)-2, 5-diphenyltetrazolium bromide
Dihydroartemisinin inhibits the Bcr/Abl oncogene at the mRNA level in chronic myeloid leukemia sensitive or resistant to imatinib
Keywords: Dihydroartemisinin; Chronic myeloid leukemia; Bcr/Abl; T315I; Imatinib-resistance
Initiation of apoptosis, cell cycle arrest and autophagy of esophageal cancer cells by dihydroartemisinin
Keywords: Dihydroartemisinin; Esophageal cancer; Autophagy; Apoptosis; Cell cycle arrestAVOs, Autophagic vacuoles; DHA, Dihydroartemisinin; PI, Propidium iodide; ROS, Reactive oxygen species; TEM, Transmission electron microscopy
Study on the developmental toxicity of combined artesunate and mefloquine antimalarial drugs on rats
Keywords: ACTs; artemisinin-containing combination therapies; bwt; body weight; oc; ossification center; DHA; dihydroartemisinin; GD; gestational day; WHO; World Health Organization; Artesunate; Mefloquine; Antimalarial; Embryolethality; Teratology; Reproductive to
Cleavage mechanism and anti-tumor activity of 3,6-epidioxy-1,10-bisaboladiene isolated from edible wild plants
Keywords: EDBD; 3,6-epidioxy-1,10-bisaboladiene; ART; artemisinin; DHA; dihydroartemisinin; DFOM; deferoxamine mesylate; γ; correlation coefficient on COMPARE Analysis; PDA; Photo Diode Array; MAPK; mitogen-activated protein kinase; CDDP; cis-diamminedichloroplati