HDAC inhibitors and neurodegeneration: At the edge between protection and damage
Keywords: اپی ژنتیک; Chromatin; Epigenetics; Brain; Neurological disorders; Myelin
مقالات ISI اپی ژنتیک (ترجمه نشده)
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Phosphorylation of the chromodomain changes the binding specificity of Cbx2 for methylated histone H3
Keywords: اپی ژنتیک; GST; glutathione S-transferase; ES; embryonic stem; PAGE; polyacrylamide gel electrophoresis; MALDI; matrix-assisted laser desorption-ionization; TOF; time-of-flight; CK2; casein kinase 2; CIAP; calf intestinal alkaline phosphatase; Epigenetics; Chromat
Targeted methylation of CMV and E1A viral promoters
Keywords: اپی ژنتیک; CMV; cytomegalovirus; E1A; early region 1A; 5-Aza; 5-aza-2â²-deoxycytidine; DNMT; DNA methyltransferase; Epigenetics; DNA methylation; Targeted DNA methylation; Viral promoter; Two-component EGFP reporter system;
Heritability of body weight: Moving beyond genetics
Keywords: اپی ژنتیک; Obesity; Genetics; Genome-wide association studies; Epigenetics
Epigenetic changes and non-coding expanded repeats
Keywords: اپی ژنتیک; Myotonic dystrophy; RNA dominance; Epigenetics; Friedreich ataxia; Fragile X syndrome; MBNL; Trinucleotide repeat
Higher order Boolean networks as models of cell state dynamics
Keywords: اپی ژنتیک; Cellular automata; Complex systems; Epigenetics; Transcription; Protein modifications
IUGR decreases PPARγ and SETD8 Expression in neonatal rat lung and these effects are ameliorated by maternal DHA supplementation
Keywords: اپی ژنتیک; DHA; Intrauterine growth restriction; Lung development; Nuclear receptor; Setd8; Epigenetics; PPARgamma
Epigenetic therapies for chemoresensitization of epithelial ovarian cancer
Keywords: اپی ژنتیک; Ovarian cancer; Epigenetics; Chemosensitization; Platinum resistance; DNMTI; HDAC inhibitor
Cell type-dependent, infection-induced, aberrant DNA methylation in gastric cancer
Keywords: اپی ژنتیک; Cancer; Computational model; DNA methylation; Epigenetics
Nuclear Matrix Association: Switching to the Invasive Cytotrophoblast
Keywords: اپی ژنتیک; Epigenetics; Trophoblast; Invasion; Nuclear matrix; Gene expression; aCGH; array Comparative Genomic Hybridization; CVS; Chorionic Villous Sampling; EVT; Extravillous Cytotrophoblasts; HTR; Human Trophoblast Cells Obtained From HTR-8/Svneo Cell Line; HTR-
Redefining regulation of DNA methylation by RNA interference
Keywords: اپی ژنتیک; DNMT, DNA methyl transferase; PcG proteins, polycomb group proteins; RNAi, RNA interference; HDAC, histone deacetylase; HAT, histone acetyl transferaseDNA methylation; Epigenetics; Transcription; RNA interference; Imprinting
Epigenetics and rheumatoid arthritis: The role of SENP1 in the regulation of MMP-1 expression
Keywords: اپی ژنتیک; Rheumatoid arthritis; MMP-1; SENP1; Histone acetylation; HDAC4; Epigenetics
Genomic loss of imprinting in first-trimester human placenta
Keywords: اپی ژنتیک; epigenetics; gene expression; loss of imprinting; placenta;
Expression of the nuclear transport protein importin ß-1 and its association with the neurokinin 3 receptor in the rat hypothalamus following acute hyperosmotic challenge
Keywords: اپی ژنتیک; GPCR; epigenetics; vasopressin; nuclear trafficking; nuclear pore; brainDTT, dithiothreitol; GPCR, G-protein coupled receptor; imp ß-1, importin ß-1; NKB, neurokinin B; NK3R, neurokinin 3 receptor; NLS, nuclear localization sequence; NPC, nuclear pore com
Novel and selective DNA methyltransferase inhibitors: Docking-based virtual screening and experimental evaluation
Keywords: اپی ژنتیک; Cancer; DNA methyltransferases; Docking; Drug discovery; Epigenetics; Structure–activity relationshipsDNMT, DNA methyltransferase; EGCG, (−)-epigallocatechin-3-gallate; HTVS, high-throughput virtual screening; moe, Molecular Operating Environment; NCI, Na
Can metal stress induce transferable changes in gene transcription in Daphnia magna?
Keywords: اپی ژنتیک; Transgenerational effect; Epigenetics; mRNA; Microarray; Zinc; Daphnia magna
Mechanisms of allergy and clinical immunologyCD14 polymorphisms and serum CD14 levels through childhood: AÂ role for gene methylation?
Keywords: اپی ژنتیک; Allergy; association study; asthma; CD14; child; cohort study; epigenetics; genetic analysis; methylation patterns; LD; Linkage disequilibrium; sCD14; Soluble CD14; SNP; Single nucleotide polymorphisms;
Long-term genistein treatment of MCF-7 cells decreases acetylated histone 3 expression and alters growth responses to mitogens and histone deacetylase inhibitors
Keywords: اپی ژنتیک; Histone deacetylase inhibitors; Histone 3; Epigenetics; Breast cancer cells; Growth; Cyclin D1; Genistein; Pro-caspase 9;
Quinazolines as novel anti-inflammatory histone deacetylase inhibitors
Keywords: اپی ژنتیک; Epigenetics; Histone deacetylase inhibitor; Chronic inflammation; Quinazolines;
An enzyme-coupled ultrasensitive luminescence assay for protein methyltransferases
Keywords: اپی ژنتیک; Epigenetics; Methyltransferase; SET7/9; S-Adenosyl-l-methionine; Luminescence;
Maternally-inherited Grb10 reduces placental size and efficiency
Keywords: اپی ژنتیک; Adapter protein; Cell signalling; Epigenetics; Genomic imprinting; Growth factor receptor-bound protein; Growth regulation; IGF; Insulin-like growth factor; Mouse; Placenta;
Genome-wide hypomethylation in cancer may be a passive consequence of transformation
Keywords: اپی ژنتیک; Epigenetics; Methylation; Cancer; Global hypomethylation
Development of homogeneous luminescence assays for histone demethylase catalysis and binding
Keywords: اپی ژنتیک; Epigenetics; Histone demethylase (HDM); JMJD2/KDM4; Fe(II) and 2-oxoglutarate (2OG) oxygenases; AlphaScreen
MicroRNA-130b regulates the tumour suppressor RUNX3 in gastric cancer
Keywords: اپی ژنتیک; RUNX3; MicroRNA; miR-130b; Gastric cancer; Tumour suppressor; Epigenetics
Primary brain tumors, neural stem cell, and brain tumor cancer cells: Where is the link?
Keywords: اپی ژنتیک; Stem cells; Cancer; Glioblastoma; Proliferation; Epigenetics
Chromatin regulation and non-coding RNAs at mammalian telomeres
Keywords: اپی ژنتیک; Telomeres; Epigenetics; TelRNA; TERRA; Telomeric chromatin; Silencing
Epigenetic mechanisms regulating CYP19 transcription in human breast adipose fibroblasts
Keywords: اپی ژنتیک; Breast cancer; Epigenetics; Aromatase; Breast adipose fibroblasts; Estrogen biosynthesis
Potential mechanisms of endogenous retroviral-mediated genomic instability in human cancer
Keywords: اپی ژنتیک; TE; transposable element; LINE; long interspersed nuclear element; SINE; short interspersed nuclear element; (H)ERV; (human) endogenous retrovirus; LTR; long terminal repeat; HML; human mammary tumor virus-like; ORF; open reading frame; DNMT; DNA methyltr
Inhibition of p300-HAT results in a reduced histone acetylation and down-regulation of gene expression in cardiac myocytes
Keywords: اپی ژنتیک; p300; Epigenetics; Histone acetylation; Cardiac myocytes; Curcumin
Chd1 remodelers maintain open chromatin and regulate the epigenetics of differentiation
Keywords: اپی ژنتیک; Epigenetics; Chromatin; Development; Chd1
Direct and transgenerational impact on Daphnia magna of chemicals with a known effect on DNA methylation
Keywords: اپی ژنتیک; 2′-deoxy-5-azacytidine; 5-azacytidine; Biochanin A; Ecotoxicology; Epigenetics; Genistein; Inheritance; Vinclozolin
Regulation of aromatase induction by nuclear receptor coregulator PELP1
Keywords: اپی ژنتیک; Estrogen; Estrogen receptor; Coregulators; Aromatase; ERRα; PELP1; Breast cancer; Epigenetics
SWI/SNF complexes, chromatin remodeling and skeletal myogenesis: It's time to exchange!
Keywords: اپی ژنتیک; Skeletal myogenesis; Transcription; Chromatin; Epigenetics; SWI/SNF
Development of novel bisubstrate-type inhibitors of histone methyltransferase SET7/9
Keywords: اپی ژنتیک; Histone methyltransferase; Small molecule inhibitor; Bisubstrate inhibitor; Epigenetics; SET7/9;
Pediatric oncology
Keywords: اپی ژنتیک; Childhood cancer; Transformation; Genetics; Epigenetics; Hereditary
Conditional inactivation of MRG15 gene function limits survival during larval and adult stages of Drosophila melanogaster
Keywords: اپی ژنتیک; Senescence; Chromatin; Epigenetics; Stem cells; Aging
Next-generation sequencing in aging research: Emerging applications, problems, pitfalls and possible solutions
Keywords: اپی ژنتیک; Bioinformatics; Epigenetics; Functional genomics; Senescence; Systems biology
Nucleosome positioning: How is it established, and why does it matter?
Keywords: اپی ژنتیک; Chromatin; Nucleosome; Epigenetics; Transcription; Genomics;
Molecular biology of cancer-associated fibroblasts: Can these cells be targeted in anti-cancer therapy?
Keywords: اپی ژنتیک; Cancer-associated fibroblast; Myofibroblast; Epigenetics; Genetics;
Fine Tuning Gene Expression: The Epigenome
Keywords: اپی ژنتیک; Epigenetics; DNA-methylation; histone modification; gene expression
Histone deacetylase inhibitors: A new perspective for the treatment of leukemia
Keywords: اپی ژنتیک; Leukemia; Epigenetics; Histone deacetylase inhibitors; Clinical trials
RAGs’ eye view of the immunoglobulin heavy chain gene locus
Keywords: اپی ژنتیک; Immunoglobulin; Enhancer; Accessibility; Epigenetics
ZAP-70 intron1 DNA methylation status: Determination by pyrosequencing in B chronic lymphocytic leukemia
Keywords: اپی ژنتیک; ZAP-70; CLL; DNA methylation; Pyrosequencing; Epigenetics
Leaf epidermal characteristics of Asiatic Buddleja L. under scanning electron microscope: Insights into chromosomal and taxonomic significance
Keywords: اپی ژنتیک; Butterfly bush; Ploidy level; Stomata dimensions; Trichome; Micromorphology; Epigenetics;
Epigenetic regulation of the expression of genes involved in steroid hormone biosynthesis and action
Keywords: اپی ژنتیک; Epigenetics; Nuclear receptors; Steroid hormones; Steroidogenesis; DNA methylation; Transcription factors
Long-term persistence of acquired resistance to 5-fluorouracil in the colon cancer cell line SW620
Keywords: اپی ژنتیک; Colon cancer; SW620, chemoresistance; 5-fluorouracil; Stem cell; Epigenetics; Transdifferentiation
DNA methylation and demethylation probed by small molecules
Keywords: اپی ژنتیک; DNA methylation; Small molecules; 5-azaC; Epigenetics; Anticancer drug; DNA demethylation; SAM; MBD2
Post-injury stress signals alter epigenetic profile of cytosine methylation in the proviral genome of endogenous retroviruses
Keywords: اپی ژنتیک; ERV; endogenous retrovirus; HERV; human endogenous retrovirus; HTDV; human teratocarcinoma-derived virus; LINE; long interspersed nuclear elements; LTR; long terminal repeat; MuERV; murine endogenous retrovirus; SINE; short interspersed nuclear elements;
Genetics and Disease Prevention: Complementary or Contradictory?
Keywords: اپی ژنتیک; disease prevention; epigenetics; family history; genetics; health promotion; human genome; metagenomics; pharmacogenomics
The role of epigenetics in environmental and occupational carcinogenesis
Keywords: اپی ژنتیک; Environmental carcinogenesis; Occupational carcinogenesis; DNA methylation; Epigenetics; Biomarkers; Cancer diagnostics; Cancer therapies